Edgar A. Jaimes, M.D.
Co-Founder and Chief Medical Officer
Dr. Jaimes is Chief of the Renal Service at Memorial Sloan Kettering Cancer Center and Professor of Medicine at Weill Cornell Medical College. His clinical work is focused on the treatment and evaluation of renal complications of cancer and its treatment, including acute kidney injury, chronic kidney disease, and electrolyte abnormalities. His research focus has been on the pathogenesis of acute and chronic kidney disease of different etiologies, where he has made major contributions to the understanding of reactive oxygen species as mediators of renal injury and the role of transcription factors such as ETS-1 in renal injury. His laboratory was the first to demonstrate that angiotensin II activates NADPH oxidase in mesangial cells and that NADPH oxidase derived reactive oxygen species promote renal injury. Dr. Jaimes’ clinical research characterized some of the risk factors that participate in the development of renal injury in patients receiving cisplatin, undergoing nephrectomy for kidney cancer, or receiving a hematogenous stem cell transplant.